Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 19/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA4 | P22748 | 5/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683134 | 0.74 | CA2 (0.51) | CA2CA1CA4CA12CA6 | |
| SCHEMBL7520641 | 0.74 | CA2 (0.62) | CA2CA1CA4 | |
| SCHEMBL9683836 | 0.73 | CA2 (0.57) | CA2CA1CA4CA12CA6 | |
| SCHEMBL9682085 | 0.71 | CA2 (0.61) | CA2CA1CA4 | |
| SCHEMBL9683786 | 0.65 | CA2 (0.61) | CA2CA1 | |
| SCHEMBL9682131 | 0.65 | CA2 (0.61) | CA2CA1CA4CA12CA6 | |
| SCHEMBL7520645 | 0.64 | CA2 (1.00) | CA2CA4 | |
| SCHEMBL9682638 | 0.63 | CA2 (0.58) | CA2CA1CA4CA12CA6 | |
| SCHEMBL9682117 | 0.61 | CA2 (0.65) | CA2CA1CA4 | |
| Hydrochloric Acid SCHEMBL9683925 | 0.61 | CA2 (0.64) | CA2CA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479480-A2 | Substituted thieno(2,3-B)(1,4)thiazine-6-sulfonamides as antiglaucoma agents | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | disclosed |