SCHEMBL9683844

SCHEMBL9683844

CCc1c(O)c(CC)c(Br)c(CC)c1Br

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38
CA4 P22748 3/20 0.38
CA6 P23280 3/20 0.38
PTPN1 P18031 1/20 0.38
DRD4 P21917 2/20 0.36
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
RECQL P46063 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAOA P21397 1/20 0.33
DRD3 P35462 1/20 0.33
GABRA1 P14867 2/20 0.31
GABRB2 P47870 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10495927 0.87 DRD4 (0.54) CA1CA2CA4CA6PTPN1
SCHEMBL10495931 0.87 CA1 (0.33) CA1CA2CA4CA6PTPN1
SCHEMBL11822745 0.86 CA1 (0.36) CA1CA2CA4CA6PTPN1
SCHEMBL10495925 0.85 CA1 (0.32) CA1CA2CA4CA6PTPN1
SCHEMBL5095740 0.84 GABRA1 (0.38) GABRA1GABRB2
SCHEMBL28482760 0.80 CA2 (0.48) CA1CA2CA4CA6PTPN1
SCHEMBL10612238 0.78 ALDH1A1 (0.38) CA1CA2CA4CA6PTPN1
SCHEMBL5589168 0.78 CA1 (0.53) CA1CA2CA4CA6PTPN1
SCHEMBL5109697 0.78 GABRA1 (0.35) CA1CA2CA4CA6PTPN1
SCHEMBL5108761 0.78 GABRA1 (0.35) CA1CA2CA4CA6PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098963-A Cresol-formaldehyde resin and 3,5-dibromo-2,4,6-trimethyl phenol for encapsulation of electronics THE DOW CHEMICAL COMPANY (US) 1992-03-24 US claimed
US-5028668-A Encapsulation of Electronics THE DOW CHEMICAL COMPANY (US) 1991-07-02 US claimed
US-4975500-A Encapsulation electronics THE DOW CHEMICAL COMPANY (US) 1990-12-04 US claimed
US-4914185-A FOR ENCAPSULATING ELECTRONIC COMPONENTS THE DOW CHEMICAL COMPANY (US) 1990-04-03 US claimed
EP-0242697-A2 Adducts of metabrominated phenols and polyfunctional epoxides THE DOW CHEMICAL COMPANY (US) 1987-10-28 EP claimed
US-5098963-A Cresol-formaldehyde resin and 3,5-dibromo-2,4,6-trimethyl phenol for encapsulation of electronics THE DOW CHEMICAL COMPANY (US) 1992-03-24 US disclosed
US-5028668-A Encapsulation of Electronics THE DOW CHEMICAL COMPANY (US) 1991-07-02 US disclosed
US-4975500-A Encapsulation electronics THE DOW CHEMICAL COMPANY (US) 1990-12-04 US disclosed
US-4914185-A FOR ENCAPSULATING ELECTRONIC COMPONENTS THE DOW CHEMICAL COMPANY (US) 1990-04-03 US disclosed
EP-0242697-A2 Adducts of metabrominated phenols and polyfunctional epoxides THE DOW CHEMICAL COMPANY (US) 1987-10-28 EP disclosed