Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35368 | 0.92 | CYP3A4 (0.53) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL29721475 | 0.90 | CYP3A4 (0.52) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL10521508 | 0.79 | CYP3A4 (0.46) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL4304103 | 0.78 | CYP3A4 (0.52) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL28685754 | 0.76 | LMNA (0.42) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL4307194 | 0.76 | CYP3A4 (0.50) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL5390273 | 0.76 | ALDH1A1 (0.50) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL4309074 | 0.76 | CYP3A4 (0.50) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL35668 | 0.76 | ADRB2 (0.45) | CYP3A4TSHRATMALDH1A1CA2 | |
| SCHEMBL6563803 | 0.76 | CYP3A4 (0.46) | CYP3A4L3MBTL1TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499206-A2 | Polyamine compositions containing secondary amine functions | NIPPON PAINT CO., LTD. (JP) | 1992-08-19 | — | — | EP | disclosed |