Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NOS2 | P35228 | 2/20 | 0.45 |
| ▸ | FADS1 | O60427 | 1/20 | 0.44 |
| ▸ | GCK | P35557 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540049 | 0.78 | RECQL (0.79) | RECQLNOS2FADS1GCKSMN1; SMN2 | |
| SCHEMBL9686366 | 0.76 | SMN1; SMN2 (0.65) | SMN1; SMN2KDM4EMAPTCYP1A2L3MBTL1 | |
| SCHEMBL9686196 | 0.75 | MAPT (0.61) | RECQLNOS2FADS1SMN1; SMN2GFER | |
| SCHEMBL25633942 | 0.74 | RECQL (0.58) | RECQLNOS2FADS1GCKSMN1; SMN2 | |
| SCHEMBL10396907 | 0.73 | MAPT (0.67) | RECQLNOS2SMN1; SMN2KMT2AALOX15 | |
| SCHEMBL3520933 | 0.73 | RECQL (0.71) | RECQLNOS2FADS1SMN1; SMN2GFER | |
| SCHEMBL9685958 | 0.73 | RECQL (0.53) | RECQLNOS2FADS1GCKSMN1; SMN2 | |
| SCHEMBL3253860 | 0.72 | RECQL (0.80) | RECQLNOS2FADS1SMN1; SMN2GFER | |
| SCHEMBL6351799 | 0.72 | RECQL (0.64) | RECQLNOS2FADS1SMN1; SMN2GFER | |
| SCHEMBL343579 | 0.72 | RECQL (0.51) | RECQLNOS2FADS1GCKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491218-A1 | Benzodiazepinones | F. HOFFMANN-LA ROCHE AG (CH) | 1992-06-24 | — | — | EP | disclosed |