Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | GABRP | O00591 | 2/20 | 0.59 |
| ▸ | GABRD | O14764 | 2/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.59 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.59 |
| ▸ | GABRE | P78334 | 2/20 | 0.59 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.59 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.59 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686042 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTCYP1A2KDM4EL3MBTL1 | |
| SCHEMBL9851289 | 0.79 | MAPT (1.00) | SMN1; SMN2MAPTCYP1A2KDM4EL3MBTL1 | |
| SCHEMBL9684143 | 0.76 | RECQL (0.53) | SMN1; SMN2MAPTCYP1A2KDM4EL3MBTL1 | |
| SCHEMBL11061295 | 0.74 | GABRP (1.00) | SMN1; SMN2MAPTCYP1A2KDM4EL3MBTL1 | |
| SCHEMBL7324248 | 0.72 | GABRP (0.75) | SMN1; SMN2MAPTCYP1A2KDM4EL3MBTL1 | |
| SCHEMBL1391455 | 0.71 | CA1 (0.65) | SMN1; SMN2MAPTCYP1A2KDM4EL3MBTL1 | |
| SCHEMBL18080781 | 0.70 | MAPT (0.78) | SMN1; SMN2MAPTCYP1A2KDM4EL3MBTL1 | |
| SCHEMBL6226752 | 0.70 | GABRP (0.57) | SMN1; SMN2MAPTCYP1A2KDM4EL3MBTL1 | |
| SCHEMBL9563516 | 0.69 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTCYP1A2KDM4EL3MBTL1 | |
| SCHEMBL21129671 | 0.68 | CYP1A2 (0.62) | SMN1; SMN2MAPTCYP1A2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491218-A1 | Benzodiazepinones | F. HOFFMANN-LA ROCHE AG (CH) | 1992-06-24 | — | — | EP | disclosed |