Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.35 |
| ▸ | GABRP | O00591 | 3/20 | 0.35 |
| ▸ | GABRD | O14764 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.35 |
| ▸ | GABRE | P78334 | 3/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684172 | 0.78 | GAA (0.40) | GAAARKDM4EALDH1A1GABRB3 | |
| SCHEMBL9730854 | 0.69 | GABRB3 (0.38) | GAAARKDM4EALDH1A1GABRB3 | |
| SCHEMBL9582428 | 0.68 | GAA (0.40) | GAAKDM4EALDH1A1GABRB3GABRA2 | |
| SCHEMBL9730755 | 0.67 | GAA (0.43) | GAAARKDM4EALDH1A1GABRB3 | |
| SCHEMBL9681975 | 0.67 | GAA (0.41) | GAAKDM4EALDH1A1GABRB3GABRA2 | |
| SCHEMBL9685317 | 0.67 | GAA (0.38) | GAAKDM4EALDH1A1GABRB3GABRA2 | |
| SCHEMBL10339152 | 0.66 | GAA (0.43) | GAAARKDM4EALDH1A1GABRB3 | |
| SCHEMBL9582286 | 0.65 | GABRA2 (0.38) | GAAKDM4EALDH1A1GABRB3GABRA2 | |
| SCHEMBL9581399 | 0.65 | GABRB3 (0.35) | GAAARKDM4EALDH1A1GABRB3 | |
| SCHEMBL9683955 | 0.65 | GAA (0.38) | GAAKDM4EALDH1A1GABRB3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481604-A1 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-22 | — | — | EP | disclosed |