Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.51 |
| ▸ | AR | P10275 | 6/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9581513 | 0.79 | AR (0.44) | AR | |
| SCHEMBL25302542 | 0.76 | KIF11 (0.50) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL30510035 | 0.76 | KIF11 (0.50) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL16894268 | 0.75 | KIF11 (0.56) | KIF11ARCYP11B2CYP11B1 | |
| SCHEMBL2167740 | 0.73 | KIF11 (0.57) | KIF11ARCYP11B2CYP11B1 | |
| SCHEMBL4595988 | 0.73 | KIF11 (0.50) | KIF11ARCYP11B2CYP11B1 | |
| SCHEMBL9730820 | 0.73 | AR (0.40) | KIF11ARCYP11B2CYP11B1 | |
| SCHEMBL29837271 | 0.72 | AR (0.47) | KIF11AR | |
| SCHEMBL384969 | 0.72 | AR (0.47) | KIF11AR | |
| SCHEMBL952338 | 0.72 | AR (0.65) | KIF11ARCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079251-A | Insecticides, pesticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-07 | — | — | US | disclosed |