Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S100B | P04271 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8754495 | 0.89 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| SCHEMBL29931735 | 0.89 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| SCHEMBL1413227 | 0.89 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL6946148 | 0.87 | CYP3A4 (0.57) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Sulfuric Acid SCHEMBL10705115 | 0.85 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Iodide SCHEMBL5582206 | 0.84 | CYP3A4 (0.53) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| SCHEMBL11441700 | 0.81 | HSD17B10 (0.44) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| SCHEMBL11655314 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Sulfuric Acid SCHEMBL3336034 | 0.81 | ALDH1A1 (0.82) | ALDH1A1CYP3A4TSHRHSD17B10L3MBTL1 | |
| Sulfuric Acid SCHEMBL9277102 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477402-A1 | Agent for determining manganese and method relating thereto | MILES INC. (US) | 1992-04-01 | — | — | EP | disclosed |