Sulfuric Acid

Sulfuric Acid

SCHEMBL10705115

CCN(O)c1cccc(N)c1.O=S(=O)(O)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 3/20 0.44
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CYP19A1 P11511 1/20 0.36
CYP3A4 P08684 4/20 0.36
CASP1 P29466 2/20 0.36
RECQL P46063 2/20 0.36
TP53 P04637 1/20 0.36
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
F2 P00734 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10369416 0.91 CYP3A4 (0.42) ALDH1A1TSHRTDP1CA12CA1
SCHEMBL11472333 0.90 CYP3A4 (0.46) ALDH1A1TSHRTDP1CA12CA1
Sulfuric Acid SCHEMBL9684336 0.85 ALDH1A1 (0.53) ALDH1A1HSD17B10TSHRTDP1LMNA
SCHEMBL11441700 0.80 HSD17B10 (0.44) ALDH1A1HSD17B10TSHRTDP1LMNA
Sulfuric Acid SCHEMBL672182 0.79 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRTDP1LMNA
Sulfuric Acid SCHEMBL9277102 0.79 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRTDP1LMNA
Sulfuric Acid SCHEMBL8754495 0.78 ALDH1A1 (0.43) ALDH1A1HSD17B10TSHRTDP1LMNA
Sulfuric Acid SCHEMBL8646873 0.78 TSHR (0.48) ALDH1A1HSD17B10TSHRCA12CA2
Sulfuric Acid SCHEMBL7767532 0.75 S100B (0.57) ALDH1A1HSD17B10TSHRTDP1LMNA
SCHEMBL4428801 0.75 POLB (0.42) ALDH1A1HSD17B10TSHRTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0137273-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1988-10-19 EP disclosed