Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 8/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 9/20 | 0.53 |
| ▸ | HTR2A | P28223 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683993 | 0.88 | ACHE (0.62) | ACHEDRD2SLC6A4HTR2CHTR2A | |
| SCHEMBL9384231 | 0.84 | DRD2 (0.64) | ACHEDRD2SLC6A4HTR2CHTR2A | |
| SCHEMBL9683889 | 0.80 | DRD2 (0.61) | ACHEDRD2SLC6A4HTR2CHTR2A | |
| SCHEMBL1545818 | 0.79 | ACHE (0.72) | ACHEDRD2SLC6A4HTR2CHTR2A | |
| SCHEMBL1545123 | 0.79 | HTR2A (0.60) | ACHEDRD2SLC6A4HTR2CHTR2A | |
| SCHEMBL9378325 | 0.76 | DRD2 (0.61) | ACHEDRD2SLC6A4HTR2CHTR2A | |
| SCHEMBL9684515 | 0.76 | HTR2A (0.56) | ACHEDRD2SLC6A4HTR2CHTR2A | |
| SCHEMBL9381946 | 0.75 | HTR2A (0.82) | ACHEDRD2SLC6A4HTR2CHTR2A | |
| SCHEMBL1545611 | 0.75 | ACHE (0.93) | ACHEDRD2SLC6A4HTR2CHTR2A | |
| SCHEMBL1544908 | 0.73 | ACHE (0.84) | ACHEDRD2SLC6A4HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134147-A | Antipsychotic agents | ADIR ET COMPAGNIE (FR) | 1992-07-28 | — | — | US | disclosed |
| US-5100902-A | Dopamine and Serotonin Antagonists, Antipsychotic Agents | ADIR ET COMPAGNIE (FR) | 1992-03-31 | — | — | US | disclosed |