SCHEMBL9684588

SCHEMBL9684588

C=C[Si](C=C)(c1ccccc1)N(c1ccccc1)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2891505 0.81
SCHEMBL328759 0.75 NPSR1 (0.33)
SCHEMBL28307829 0.73 ESR1 (0.33)
SCHEMBL25883862 0.70 KMT2A (0.34) ALDH1A1TSHR
SCHEMBL9684586 0.68
SCHEMBL2891504 0.67 NPSR1 (0.30)
SCHEMBL10664430 0.63 NPSR1 (0.30)
SCHEMBL7633250 0.62
SCHEMBL26255252 0.62 KMT2A (0.39) ALDH1A1TSHR
SCHEMBL453982 0.61 NR1H2 (0.48) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110117357-B Silane modified polyether and preparation method thereof 浙江新安化工集团股份有限公司 2020-04-03 CN claimed
US-5124283-A Hardening of fusible polysilazanes and SiC/Si3 N4 ceramics produced therefrom RHONE-POULENC CHIMIE (FR) 1992-06-23 US disclosed
EP-0209472-B1 PROCESS FOR THE HEAT TREATMENT OF A POLYSILAZANE HAVING SINH, SI-H AND UNSATURATED GROUPS RHONE-POULENC CHIMIE (FR) 1991-09-25 EP disclosed
EP-0448432-A1 Method of forming ceramic coatings on carbon-substrates RHONE-POULENC CHIMIE (FR) 1991-09-25 EP disclosed
US-5037933-A Contacting with ion exchange material RHONE-POULENC CHIMIE (FR) 1991-08-06 US disclosed
US-5017640-A ADSORBENT FOR CATALYST RHONE-POULENC CHIMIE (FR) 1991-05-21 US disclosed
EP-0424279-A1 Process for preparing high molecular weight polyorganosilazanes RHONE-POULENC CHIMIE (FR) 1991-04-24 EP disclosed
EP-0412915-A1 Wet process for crosslinking polysilazanes for producing ceramic fibres RHONE-POULENC CHIMIE (FR) 1991-02-13 EP disclosed
EP-0412914-A1 Process for crosslinking polysilazanes for the production of ceramic fibrers RHONE-POULENC CHIMIE (FR) 1991-02-13 EP disclosed
EP-0384793-A1 Process for curing polysilazanes RHONE-POULENC CHIMIE (FR) 1990-08-29 EP disclosed
US-4722988-A Organopolysilazane composition containing free radical generators and capable of being crosslinked by an energy input RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1988-02-02 US disclosed
US-4694060-A PRECURSORS FOR CERAMICS RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1987-09-15 US disclosed
EP-0235485-A1 Process for treating a polysilazane with at least two aliphatically unsaturated groups in the presence of a catalyst RHONE-POULENC CHIMIE (FR) 1987-09-09 EP disclosed
US-4689252-A FORMS CERAMIC WHEN PYROLYZED, IMPREGNATING SUBSTRATES RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1987-08-25 US disclosed
US-4689382-A POLYMERIZATION WITH ACID CATALYST RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1987-08-25 US disclosed
US-4656300-A Process for a thermal treatment of a polysilazane containing .tbd.SiH groups and .tbd.Si--NH-- groups RHONE POULENC SPECIALITES CHIMIQUES (FR) 1987-04-07 US disclosed
EP-0208630-A1 Process for treating a polysilazane having at least two =/- SiH groups with a cationic catalyst RHONE-POULENC CHIMIE (FR) 1987-01-14 EP disclosed
EP-0202176-A1 Process for treating polyorganosilazanes and/or polyorgano(disilyl)silazanes with a catalyst comprising a mineral ionic salt and a complexing agent RHONE-POULENC CHIMIE (FR) 1986-11-20 EP disclosed
EP-0197863-A1 Process for preparing organosilazanes and organopoly(disilyl)silazanes with an enhanced heat stability, and their use in preparing ceramic materials RHONE-POULENC CHIMIE (FR) 1986-10-15 EP disclosed
US-4152315-A TREATING SILICA FILLER IN SITU, EASILY EXTRUDABLE SILICONES WHICH CURE TO TRANSPARENT ELASTOMERS DOW CORNING CORPORATION (US) 1979-05-01 US disclosed