SCHEMBL2891504

SCHEMBL2891504

C=C[SiH](C=C)N(c1ccccc1)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9684586 0.81
SCHEMBL328759 0.74 NPSR1 (0.33) NPSR1
SCHEMBL133920 0.72 NPSR1 (0.32) NPSR1
SCHEMBL10664430 0.69 NPSR1 (0.30) NPSR1
SCHEMBL9684588 0.67 ALDH1A1 (0.31)
SCHEMBL2891505 0.66
SCHEMBL18421610 0.65 ESR1 (0.31)
SCHEMBL14369578 0.65 ALDH1A1 (0.35) NPSR1
SCHEMBL2463903 0.63 ALDH1A1 (0.33) NPSR1
SCHEMBL28307829 0.60 ESR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2178889-B1 CURABLE AND CURED SILICONE RUBBER COMPOSITIONS AND METHODS FOR THEIR PREPARATION USING FUNCTIONALISED SILICA MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-02 EP disclosed
US-8501856-B2 Curable silicon-containing compositions possessing high translucency MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-08-06 US disclosed
US-7790829-B2 Curable and cured silicone rubber compositions and methods therefor MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-09-07 US disclosed
EP-2178983-A2 CURABLE SILICON-CONTAINING COMPOSITIONS POSSESSING HIGH TRANSLUCENCY Momentive Performance Materials Inc. (US) 2010-04-28 EP disclosed
EP-2178889-A1 CURABLE AND CURED SILICONE RUBBER COMPOSITIONS AND METHODS FOR THEIR PREPARATION USING FUNCTIONALISED SILICA Momentive Performance Materials Inc. (US) 2010-04-28 EP disclosed
WO-2009011777-A2 CURABLE SILICON-CONTAINING COMPOSITIONS POSSESSING HIGH TRANSLUCENCY MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-01-22 WO disclosed
WO-2009011779-A1 CURABLE AND CURED SILICONE RUBBER COMPOSITIONS AND METHODS FOR THEIR PREPARATION USING FUNCTIONALISED SILICA MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-01-22 WO disclosed
US-20090018260-A1 Curable silicon-containing compositions possessing high translucency MOMENTIVE PERFORMANCE MATERIALS INC. 2009-01-15 US disclosed
US-20090018261-A1 Curable and cured silicone rubber compositions and methods therefor MOMENTIVE PERFORMANCE MATERIALS, INC. 2009-01-15 US disclosed