Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686157 | 0.90 | NPSR1 (0.55) | PRMT1TRPA1PTPN11LMNAHTT | |
| SCHEMBL9685436 | 0.89 | PRMT1 (0.51) | PRMT1TRPA1PTPN11LMNAHTT | |
| SCHEMBL9298122 | 0.89 | PRMT1 (0.51) | PRMT1TRPA1PTPN11LMNAHTT | |
| SCHEMBL9685366 | 0.88 | PTPN11 (0.59) | PRMT1TRPA1PTPN11LMNAALDH1A1 | |
| SCHEMBL8812552 | 0.88 | ALOX15 (0.51) | PRMT1TRPA1PTPN11LMNAHTT | |
| SCHEMBL9685091 | 0.86 | TRPA1 (0.59) | PRMT1TRPA1PTPN11LMNAHTT | |
| SCHEMBL9686678 | 0.85 | TRPA1 (0.56) | PRMT1TRPA1PTPN11LMNAHTT | |
| SCHEMBL11870333 | 0.83 | TRPA1 (0.46) | PRMT1TRPA1PTPN11LMNAHTT | |
| SCHEMBL8808999 | 0.83 | HTT (0.46) | PRMT1TRPA1LMNAHTTALDH1A1 | |
| SCHEMBL8811292 | 0.83 | TRPA1 (0.49) | PRMT1TRPA1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188094-B1 | QUINAZOLINE DERIVATIVES AND ANTIHYPERTENSIVE PREPARATIONS CONTAINING SAME AS EFFECTIVE COMPONENTS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4734418-A | Quinazoline compounds and antihypertensives | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0188094-A2 | Quinazoline derivatives and antihypertensive preparations containing same as effective components | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |