Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | PRCP | P42785 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332110 | 0.88 | OPRM1 (0.57) | OPRM1OPRK1OPRD1OPRL1MTNR1B | |
| SCHEMBL4856422 | 0.84 | OPRM1 (0.57) | OPRM1OPRK1OPRD1OPRL1MTNR1B | |
| SCHEMBL14559376 | 0.81 | OPRM1 (0.71) | OPRM1OPRK1OPRD1OPRL1MTNR1B | |
| SCHEMBL8024199 | 0.79 | PRCP (0.56) | OPRM1OPRK1OPRD1OPRL1MTNR1B | |
| SCHEMBL21890121 | 0.79 | PRCP (0.56) | OPRM1OPRK1OPRD1OPRL1MTNR1B | |
| SCHEMBL23057928 | 0.79 | PRCP (0.56) | OPRM1OPRK1OPRD1OPRL1MTNR1B | |
| Hydrochloric Acid SCHEMBL10640981 | 0.78 | OPRM1 (0.54) | OPRM1OPRK1OPRD1OPRL1MTNR1B | |
| SCHEMBL3255532 | 0.78 | PRCP (0.54) | OPRM1OPRK1OPRD1OPRL1PRCP | |
| SCHEMBL3245156 | 0.78 | KCNN2 (0.55) | OPRM1OPRK1OPRD1OPRL1PRCP | |
| SCHEMBL30952114 | 0.78 | PRCP (0.54) | OPRM1OPRK1OPRD1OPRL1MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128369-A | Antiallergens, bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |