SCHEMBL9684741

SCHEMBL9684741

CC(=O)OCc1ccccc1C.COC(OC)c1ccccc1C

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.43
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
KDM4E B2RXH2 3/20 0.41
HSD17B10 Q99714 1/20 0.41
LMNA P02545 2/20 0.40
MAPT P10636 3/20 0.38
ADORA2A P29274 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.36
FFAR1 O14842 2/20 0.36
FPR2 P25090 1/20 0.36
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1984327 0.84 ALDH1A1 (0.57) MAOBALDH1A1SMN1; SMN2KDM4EHSD17B10
SCHEMBL30417552 0.84 ALDH1A1 (0.57) MAOBALDH1A1SMN1; SMN2KDM4EHSD17B10
O-Xylene SCHEMBL9685099 0.83 ALDH1A1 (0.55) MAOBALDH1A1SMN1; SMN2KDM4EHSD17B10
SCHEMBL9685864 0.79 ALDH1A1 (0.47) MAOBALDH1A1SMN1; SMN2KDM4ELMNA
SCHEMBL3206497 0.76 ESR1 (0.56) ALDH1A1LMNACYP3A4
SCHEMBL5255523 0.74 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2KDM4EHSD17B10LMNA
SCHEMBL8214225 0.74 FABP4 (0.50) ALDH1A1SMN1; SMN2KDM4EHSD17B10LMNA
SCHEMBL10583241 0.73 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2KDM4EHSD17B10MAPT
SCHEMBL15853342 0.73 MAOB (0.51) MAOBALDH1A1SMN1; SMN2KDM4EHSD17B10
SCHEMBL4231829 0.73 ALDH1A1 (0.52) MAOBALDH1A1KDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5078838-A By electrochemical anodic oxidation of benzyl derivatives in the presence of an aliphatic alcohol BASF AKTIENGESELLSCHAFT (DE) 1992-01-07 US disclosed