SCHEMBL9685864

SCHEMBL9685864

CC(=O)OCc1ccccc1F.COC(OC)c1ccccc1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
LMNA P02545 3/20 0.47
KDM4E B2RXH2 1/20 0.47
MAOB P27338 2/20 0.45
NPC1 O15118 6/20 0.43
RAB9A P51151 5/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
ATM Q13315 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP12 P39900 1/20 0.42
TSHR P16473 2/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3231685 0.85 ALDH1A1 (0.59) ALDH1A1LMNAKDM4EMAOBNPC1
SCHEMBL9684741 0.79 MAOB (0.43) ALDH1A1LMNAKDM4EMAOBL3MBTL1
SCHEMBL9685815 0.78 ALDH1A1 (0.52) ALDH1A1LMNAKDM4EMAOBNPC1
SCHEMBL9019981 0.76 IDO1 (0.42) ALDH1A1LMNAKDM4EL3MBTL1MAPT
SCHEMBL19765221 0.74 ALDH1A1 (0.54) ALDH1A1LMNAKDM4EMAOBNPC1
SCHEMBL5255523 0.73 ALDH1A1 (0.65) ALDH1A1LMNAKDM4ERAB9AL3MBTL1
SCHEMBL8214225 0.72 FABP4 (0.50) ALDH1A1LMNAKDM4ERAB9AL3MBTL1
SCHEMBL3827328 0.72 ALDH1A1 (0.47) ALDH1A1LMNAKDM4EMAOBNPC1
SCHEMBL10583241 0.72 ALDH1A1 (0.52) ALDH1A1KDM4EL3MBTL1SMN1; SMN2MAPT
SCHEMBL27918522 0.72 MEN1 (0.50) ALDH1A1LMNAKMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5078838-A By electrochemical anodic oxidation of benzyl derivatives in the presence of an aliphatic alcohol BASF AKTIENGESELLSCHAFT (DE) 1992-01-07 US disclosed