SCHEMBL9684759

SCHEMBL9684759

CC(=O)OCc1ccc(-c2ccc(C)cc2)cc1.COC(OC)c1ccc(-c2ccc(C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
MMP12 P39900 3/20 0.39
MAOB P27338 1/20 0.39
CYP3A4 P08684 1/20 0.38
MMP2 P08253 2/20 0.38
MMP1 P03956 1/20 0.38
MMP9 P14780 1/20 0.38
PKM P14618 1/20 0.37
NPBWR1 P48145 1/20 0.37
MCHR1 Q99705 1/20 0.37
FFAR1 O14842 3/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
P2RX4 Q99571 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9686517 0.86 ALDH1A1 (0.60) ALDH1A1MMP12MAOBCYP3A4MMP2
SCHEMBL9687590 0.86 ALDH1A1 (0.60) ALDH1A1MMP12MAOBCYP3A4MMP2
SCHEMBL9686479 0.82 ALDH1A1 (0.49) ALDH1A1MMP12MAOBCYP3A4MMP2
SCHEMBL18622513 0.81 ALDH1A1 (0.47) ALDH1A1MMP12MAOBCYP3A4MMP2
P-Xylene SCHEMBL9685877 0.81 ALDH1A1 (0.67) ALDH1A1MMP12MAOBCYP3A4MMP2
SCHEMBL873414 0.81 ALDH1A1 (0.67) ALDH1A1MMP12MAOBCYP3A4MMP2
SCHEMBL4198688 0.79 ALDH1A1 (0.69) ALDH1A1CYP3A4NPC1RAB9A
SCHEMBL14063397 0.78 ALDH1A1 (0.50) ALDH1A1MMP12MAOBCYP3A4MMP2
SCHEMBL9321763 0.78 CHRNA7 (0.39) ALDH1A1FFAR1NPC1RAB9A
SCHEMBL12518683 0.76 ALDH1A1 (0.60) ALDH1A1CYP3A4NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5078838-A By electrochemical anodic oxidation of benzyl derivatives in the presence of an aliphatic alcohol BASF AKTIENGESELLSCHAFT (DE) 1992-01-07 US disclosed