Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684808 | 1.00 | CYP2C19 (0.56) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL3112777 | 0.82 | CYP2C19 (0.47) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL12496748 | 0.82 | MEN1 (0.41) | CYP2C19HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16830005 | 0.80 | HPGD (0.39) | CYP2C19KMT2AHTTPRSS1CTSG | |
| SCHEMBL2065478 | 0.80 | MEN1 (0.50) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL12393357 | 0.79 | MAPT (0.46) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL5142176 | 0.78 | CYP2C19 (0.56) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL7075423 | 0.78 | KIF11 (0.44) | CYP2C19HIF1AHDAC3HDAC4HDAC1 | |
| SCHEMBL8588291 | 0.77 | KMT2A (0.47) | CYP2C19HIF1AKMT2AMEN1HTT | |
| SCHEMBL6017656 | 0.77 | NPC1 (0.52) | CYP2C19LMNARAB9AHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513703-A2 | Carbamate esters of eseroline having anticholinesterase activity, a process for their preparation and relative pharmaceutical compositions containing them as the active principle | MAGIS FARMACEUTICI S.p.A. (IT) | 1992-11-19 | — | — | EP | disclosed |