Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588291 | 0.82 | KMT2A (0.47) | SIGMAR1HTTCYP2C19 | |
| SCHEMBL9684810 | 0.77 | CYP2C19 (0.56) | RAB9APOLBHTTCYP2C19LMNA | |
| SCHEMBL9684808 | 0.77 | CYP2C19 (0.56) | RAB9APOLBHTTCYP2C19LMNA | |
| SCHEMBL1116608 | 0.76 | HPGD (0.57) | NPC1RAB9AHPGDCYP1A2POLB | |
| SCHEMBL31275700 | 0.76 | HPGD (0.57) | NPC1RAB9AHPGDCYP1A2POLB | |
| SCHEMBL5643015 | 0.75 | POLB (0.55) | NPC1RAB9AHPGDCYP1A2POLB | |
| SCHEMBL4148749 | 0.74 | HPGD (0.70) | NPC1RAB9AHPGDCYP1A2POLB | |
| SCHEMBL8591090 | 0.73 | RAB9A (0.49) | NPC1RAB9APOLBCYP2C19LMNA | |
| SCHEMBL2490818 | 0.73 | RAB9A (0.63) | NPC1RAB9AHPGDCYP1A2POLB | |
| SCHEMBL10605231 | 0.72 | POLB (0.64) | NPC1RAB9AHPGDCYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429783-A4 | MULTI-USE MULTIMODAL IMAGING CHELATES | UNIV TEXAS TECH (US) | 2006-08-09 | — | — | EP | disclosed |
| EP-1429783-A2 | MULTI-USE MULTIMODAL IMAGING CHELATES | TEXAS TECH UNIVERSITY (US) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003020701-A9 | MULTI-USE MULTIMODAL IMAGING CHELATES | UNIV TEXAS TECH (US) | 2003-09-12 | — | — | WO | disclosed |
| WO-2003020701-A2 | MULTI-USE MULTIMODAL IMAGING CHELATES | TEXAS TECH UNIVERSITY (US) | 2003-03-13 | — | — | WO | disclosed |