SCHEMBL9684853

SCHEMBL9684853

O=C(O)c1cc(Cl)cnc1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
TP53 P04637 1/20 0.45
KDM4E B2RXH2 4/20 0.44
CYP3A4 P08684 2/20 0.44
TSHR P16473 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
HCAR2 Q8TDS4 1/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
BLM P54132 1/20 0.44
AGER Q15109 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
AKR1C4 P17516 1/20 0.44
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44
AKR1C1 Q04828 1/20 0.44
DHODH Q02127 2/20 0.42
DYRK1A Q13627 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952418 0.86 HCAR2 (0.40) ALDH1A1TP53KDM4ECYP3A4TSHR
SCHEMBL8660093 0.85 ALDH1A1 (0.40) ALDH1A1TP53KDM4ECYP3A4TSHR
SCHEMBL16011722 0.83 BACE1 (0.39) ALDH1A1TP53KDM4ECYP3A4TSHR
SCHEMBL287761 0.81 LMNA (0.47) ALDH1A1TP53TSHRL3MBTL1HCAR2
SCHEMBL29378297 0.81 SMN1; SMN2 (0.48) ALDH1A1TP53KDM4ECYP3A4TSHR
SCHEMBL915781 0.81 SMN1; SMN2 (0.48) ALDH1A1TP53KDM4ECYP3A4TSHR
SCHEMBL23413510 0.79 LMNA (0.46) ALDH1A1TP53TSHRL3MBTL1HCAR2
SCHEMBL8514986 0.79 SPR (0.48) ALDH1A1KDM4EL3MBTL1HCAR2CA1
Hydrochloric Acid SCHEMBL20139726 0.79 LMNA (0.46) ALDH1A1TP53TSHRL3MBTL1HCAR2
SCHEMBL329752 0.79 CA1 (0.48) ALDH1A1TP53KDM4ECYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590343-B2 Corrosion inhibitor composition for magnesium or magnesium alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2020-03-17 US claimed
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP claimed
EP-3284847-A1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2018-02-21 EP claimed
US-20180044590-A1 Corrosion Inhibitor Composition for Magnesium or Magnesium Alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2018-02-15 US claimed
US-20240190874-A1 SMALL MOLECULE DEGRADERS OF ANDROGEN RECEPTOR THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-06-13 US disclosed
WO-2022187419-A1 SMALL MOLECULE DEGRADERS OF ANDROGEN RECEPTOR THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-09-09 WO disclosed
US-10590343-B2 Corrosion inhibitor composition for magnesium or magnesium alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2020-03-17 US disclosed
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP disclosed
EP-3284847-A1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2018-02-21 EP disclosed
US-20180044590-A1 Corrosion Inhibitor Composition for Magnesium or Magnesium Alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2018-02-15 US disclosed
US-5122608-A Hydrolysis ofa 2,3-pyridine- or quinolinedicarboxylic acid diester with water and a acid having an ionization constant of 3; treating with a base and separating AMERICAN CYANAMID COMPANY (US) 1992-06-16 US disclosed
EP-0259687-B1 METHOD FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC ACIDS AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP disclosed
US-4816588-A OXIDATION OF 8-SUBSTITUTED QUINOLINES AMERICAN CYANAMID COMPANY (US) 1989-03-28 US disclosed
EP-0259687-A2 Method for the preparation of pyridine-2,3-dicarboxylic acids AMERICAN CYANAMID COMPANY (US) 1988-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240190874-A1 SMALL MOLECULE DEGRADERS OF ANDROGEN RECEPTOR AR, CYP19A1, ESRRA ALDH1A1 231/4885TP53 36/4885KDM4E 1652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.