Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 7/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684877 | 1.00 | ADRB1 (0.51) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL9685473 | 0.88 | ADRB1 (0.50) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL9685479 | 0.88 | ADRB1 (0.50) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL9685400 | 0.85 | ADRB1 (0.47) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL9685304 | 0.83 | ATM (0.45) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL9685296 | 0.83 | ATM (0.45) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL10551613 | 0.82 | ALDH1A1 (0.51) | ADRB1ADRB3ADRB2CYP1A2CYP3A4 | |
| SCHEMBL10551624 | 0.82 | ALDH1A1 (0.51) | ADRB1ADRB3ADRB2CYP1A2CYP3A4 | |
| SCHEMBL10551629 | 0.82 | ALDH1A1 (0.51) | ADRB1ADRB3ADRB2CYP1A2CYP3A4 | |
| SCHEMBL9685069 | 0.81 | ADRB1 (0.54) | ADRB1ADRB3ADRB2ATMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |