Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | PREP | P48147 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257373 | 0.85 | CTSB (0.54) | CTSKCTSBCTSLCTSS | |
| SCHEMBL10867951 | 0.79 | CTSK (0.50) | CTSKCTSBCTSLCTSSPREP | |
| SCHEMBL28222679 | 0.79 | CTSK (0.50) | CTSKCTSBCTSLCTSSPREP | |
| SCHEMBL2083582 | 0.78 | ALDH1A1 (0.49) | CTSKCTSBCTSLCTSSPREP | |
| SCHEMBL1660941 | 0.78 | HPGD (0.49) | ATMELANE | |
| SCHEMBL9186562 | 0.75 | ALDH1A1 (0.44) | KMT2AELANECYP3A4 | |
| SCHEMBL15081415 | 0.75 | CYP1A2 (0.56) | CTSKCTSBCTSLCTSSPREP | |
| SCHEMBL28060962 | 0.75 | CYP1A2 (0.56) | CTSKCTSBCTSLCTSSPREP | |
| SCHEMBL15080869 | 0.74 | CTSK (0.61) | CTSKCTSBCTSLCTSSMEN1 | |
| SCHEMBL241565 | 0.74 | CTSK (0.61) | CTSKCTSBCTSLCTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1066656-A | The Pyridione derivatives that amino acid azelidinyl replaces, its preparation method and as the application of medicine | ESTEVE LABOR DR (ES) | 1992-12-02 | — | — | CN | disclosed |
| EP-0514268-A1 | Substituted amino acid azetidinyl pyridone derivatives, their preparation and use as medicines | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-11-19 | — | — | EP | disclosed |