Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | OGT | O15294 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647933 | 0.84 | ALDH1A1 (0.60) | ALDH1A1CREBBPKDM4EPDE3BPDE3A | |
| SCHEMBL17260664 | 0.77 | KDM4E (0.62) | ALDH1A1CREBBPKDM4ESMYD3NOS1 | |
| SCHEMBL14565010 | 0.76 | NOS1 (0.52) | ALDH1A1CREBBPKDM4ESMYD3NOS1 | |
| SCHEMBL9682938 | 0.76 | TOP2A (0.51) | ALDH1A1CREBBPKDM4EPDE3BPDE3A | |
| SCHEMBL858860 | 0.76 | CREBBP (0.48) | ALDH1A1CREBBPKDM4EPDE3BPDE3A | |
| SCHEMBL9484144 | 0.76 | MAP2K1 (0.48) | ALDH1A1PDE3BPDE3AMAP2K1ESR1 | |
| SCHEMBL9470246 | 0.75 | MAP2K1 (0.47) | ALDH1A1MAP2K1JAK3APPGAA | |
| SCHEMBL29771053 | 0.75 | KDM4E (0.67) | ALDH1A1CREBBPKDM4EPDE3BPDE3A | |
| SCHEMBL118684 | 0.75 | KDM4E (0.67) | ALDH1A1CREBBPKDM4EPDE3BPDE3A | |
| SCHEMBL30494348 | 0.74 | PDE3B (0.70) | ALDH1A1PDE3BPDE3ANOS1OGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463944-B1 | Acylbenzoxazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-10-05 | — | — | EP | disclosed |
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |
| EP-0463944-A1 | Acylbenzoxazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-01-02 | — | — | EP | disclosed |