Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686336 | 0.81 | ALDH1A1 (0.49) | IDO1SMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL9686196 | 0.77 | MAPT (0.61) | IDO1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9540049 | 0.77 | RECQL (0.79) | RECQLSMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL9519121 | 0.77 | RECQL (0.51) | IDO1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9685958 | 0.75 | RECQL (0.53) | IDO1RECQLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7507358 | 0.74 | GAA (0.55) | IDO1SMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL9686216 | 0.74 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1TP53RAB9AKMT2A | |
| SCHEMBL28060 | 0.72 | RECQL (0.57) | RECQLSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL31366630 | 0.72 | RECQL (0.57) | RECQLSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL28232 | 0.72 | CCR9 (0.58) | RECQLSMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491218-A1 | Benzodiazepinones | F. HOFFMANN-LA ROCHE AG (CH) | 1992-06-24 | — | — | EP | disclosed |