Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787241 | 0.86 | MEN1 (0.64) | MEN1KMT2AALDH1A1ADRB1CYP2D6 | |
| SCHEMBL9787233 | 0.86 | MEN1 (0.64) | MEN1KMT2AALDH1A1ADRB1CYP2D6 | |
| SCHEMBL10792807 | 0.82 | ADRB1 (0.67) | MEN1KMT2AADRB1CYP2D6ADRB2 | |
| Hydrochloric Acid SCHEMBL10790452 | 0.81 | ADRB1 (0.66) | MEN1KMT2AADRB1CYP2D6ADRB2 | |
| SCHEMBL9684232 | 0.80 | ABCB1 (0.48) | MEN1KMT2AALDH1A1CASRADRB1 | |
| SCHEMBL9684871 | 0.79 | ADRB1 (0.58) | MEN1KMT2AALDH1A1ADRB1ADRB2 | |
| SCHEMBL9684876 | 0.79 | ADRB1 (0.58) | MEN1KMT2AALDH1A1ADRB1ADRB2 | |
| SCHEMBL11097637 | 0.79 | CYP2D6 (0.67) | MEN1KMT2AALDH1A1CASRADRB1 | |
| Hydrochloric Acid SCHEMBL10791088 | 0.78 | CYP2D6 (0.66) | MEN1KMT2AALDH1A1CASRADRB1 | |
| SCHEMBL10789731 | 0.74 | ADRB1 (0.70) | MEN1KMT2AADRB1CYP2D6ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |