Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787241 | 1.00 | MEN1 (0.64) | MEN1KMT2AALDH1A1ADRB1ADRB2 | |
| SCHEMBL10792807 | 0.88 | ADRB1 (0.67) | MEN1KMT2AADRB1ADRB2ADRB3 | |
| Hydrochloric Acid SCHEMBL10790452 | 0.86 | ADRB1 (0.66) | MEN1KMT2AADRB1ADRB2ADRB3 | |
| SCHEMBL9685227 | 0.86 | MEN1 (0.51) | MEN1KMT2AALDH1A1ADRB1ADRB2 | |
| SCHEMBL9682895 | 0.82 | ADRB3 (0.65) | MEN1KMT2AALDH1A1ADRB1ADRB2 | |
| SCHEMBL9682885 | 0.82 | ADRB3 (0.65) | MEN1KMT2AALDH1A1ADRB1ADRB2 | |
| SCHEMBL9684048 | 0.81 | ADRB3 (0.87) | MEN1KMT2AALDH1A1ADRB1ADRB2 | |
| SCHEMBL9685312 | 0.81 | ADRB3 (0.87) | MEN1KMT2AALDH1A1ADRB1ADRB2 | |
| SCHEMBL9684040 | 0.81 | ADRB3 (0.87) | MEN1KMT2AALDH1A1ADRB1ADRB2 | |
| SCHEMBL9684232 | 0.80 | ABCB1 (0.48) | MEN1KMT2AALDH1A1ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |