Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656937 | 0.78 | TSHR (0.59) | POLBGSK3BGSK3AMAPTSMN1; SMN2 | |
| SCHEMBL9685245 | 0.76 | MAPT (0.58) | POLBGSK3BMAPTSMN1; SMN2KMT2A | |
| SCHEMBL15030421 | 0.73 | MAPT (0.55) | POLBGSK3BGSK3AMAPTSMN1; SMN2 | |
| SCHEMBL23505897 | 0.72 | AOC3 (0.42) | POLBMAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL21650573 | 0.70 | HDAC6 (0.53) | MCHR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL31014872 | 0.70 | HTR2A (0.35) | POLBMAPTKMT2AMEN1LMNA | |
| SCHEMBL28115922 | 0.70 | KDM4E (0.57) | GSK3BGSK3AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL15030482 | 0.70 | MEN1 (0.54) | POLBGSK3BGSK3AMAPTSMN1; SMN2 | |
| SCHEMBL20042582 | 0.70 | SMN1; SMN2 (0.56) | GSK3BMAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL5093410 | 0.70 | ALDH1A1 (0.53) | POLBMAPTSMN1; SMN2MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515893-A1 | Substituted 4-heteroarylpyrazolines | BAYER AG (DE) | 1992-12-02 | — | — | EP | disclosed |