Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.31 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20346803 | 0.86 | GAA (0.37) | POLBSMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL16443634 | 0.81 | ELANE (0.33) | POLBSMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL9858280 | 0.78 | GAA (0.31) | GAA | |
| SCHEMBL15524422 | 0.77 | GAA (0.36) | POLBSMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL2564897 | 0.77 | GAA (0.36) | POLBSMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL24307921 | 0.74 | BTN3A1 (0.35) | POLBSMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL14699971 | 0.73 | PLA2G1B (0.34) | POLBSMN1; SMN2ALDH1A1MAPTGAA | |
| SCHEMBL9684363 | 0.73 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL10448217 | 0.72 | POLB (0.32) | POLBSMN1; SMN2 | |
| SCHEMBL9684136 | 0.70 | POLB (0.34) | POLBSMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |