SCHEMBL9858280

SCHEMBL9858280

CCOP(=O)(COCC(CO[Si](C)(C)C(C)(C)C)ON1C(=O)c2ccccc2C1=O)OCC

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20346803 0.85 GAA (0.37) GAA
SCHEMBL9685262 0.78 POLB (0.32) GAA
SCHEMBL9858000 0.77 TSHR (0.31)
SCHEMBL9684136 0.76 POLB (0.34) GAA
SCHEMBL9858037 0.76 TSHR (0.30)
SCHEMBL2564897 0.75 GAA (0.36) GAA
SCHEMBL15524422 0.75 GAA (0.36) GAA
SCHEMBL9858388 0.74 ABCB11 (0.34)
SCHEMBL10439456 0.74 GAA (0.33) GAAELANE
SCHEMBL16443634 0.72 ELANE (0.33) GAAELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5055458-A PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY BEECHAM GROUP P.L.C. (GB) 1991-10-08 US disclosed
EP-0353955-A2 Novel compounds BEECHAM GROUP PLC (GB) 1990-02-07 EP disclosed