Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10439456 | 0.89 | GAA (0.33) | POLBSMN1; SMN2GAAMEN1MAPT | |
| SCHEMBL9684455 | 0.80 | POLB (0.38) | POLBSMN1; SMN2GAAMAPT | |
| SCHEMBL9858280 | 0.76 | GAA (0.31) | GAA | |
| SCHEMBL9683709 | 0.76 | PPARD (0.34) | — | |
| SCHEMBL7123164 | 0.76 | GAA (0.34) | POLBSMN1; SMN2GAAMEN1MAPT | |
| SCHEMBL7123159 | 0.76 | GAA (0.37) | POLBSMN1; SMN2GAAMEN1MAPT | |
| SCHEMBL9683342 | 0.74 | PPARD (0.41) | — | |
| SCHEMBL14439985 | 0.72 | GAA (0.54) | GAA | |
| SCHEMBL9683433 | 0.71 | FAP (0.35) | — | |
| SCHEMBL9685502 | 0.71 | FDPS (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |