SCHEMBL9685263

SCHEMBL9685263

CCSC(=O)c1c(O)cccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
BCL2L1 Q07817 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ADORA3 P0DMS8 12/20 0.43
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
FOLH1 Q04609 1/20 0.41
HNF4A P41235 1/20 0.40
KMT2A Q03164 1/20 0.39
THRB P10828 1/20 0.39
TRPV1 Q8NER1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7755630 0.78 ALDH1A1 (0.44) ALDH1A1HPGDBCL2L1HSD17B10CA12
SCHEMBL7754530 0.76 ALDH1A1 (0.54) ALDH1A1HPGDBCL2L1HSD17B10ADORA3
SCHEMBL15509403 0.76 THRB (0.63) ALDH1A1HPGDBCL2L1HSD17B10CA12
SCHEMBL3264678 0.76 CA12 (0.64) ALDH1A1HPGDBCL2L1HSD17B10CA12
SCHEMBL4320540 0.75 CA12 (0.72) ALDH1A1HPGDHSD17B10ADORA3CA12
SCHEMBL9567431 0.73 CA12 (0.46) ALDH1A1HPGDBCL2L1HSD17B10CA12
SCHEMBL975812 0.73 BCAT2 (0.55) ALDH1A1HPGDBCL2L1HSD17B10CA12
SCHEMBL5471293 0.72 ALDH1A1 (0.48) ALDH1A1HPGDBCL2L1HSD17B10CA12
SCHEMBL9049651 0.72 CA12 (0.69) ALDH1A1HPGDBCL2L1HSD17B10CA12
SCHEMBL28939785 0.72 CA12 (0.45) ALDH1A1HPGDBCL2L1HSD17B10CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100458-A Pyrimidine substituted, plant growth regulators BASF AKTIENGESELLSCHAFT (DE) 1992-03-31 US disclosed