Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 11/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684201 | 0.87 | ADRB3 (0.64) | ADRB1ADRB3ADRB2MEN1ALDH1A1 | |
| SCHEMBL9684195 | 0.87 | ADRB3 (0.64) | ADRB1ADRB3ADRB2MEN1ALDH1A1 | |
| SCHEMBL9812077 | 0.87 | ADRB3 (0.64) | ADRB1ADRB3ADRB2MEN1ALDH1A1 | |
| SCHEMBL9684241 | 0.85 | ADRB1 (0.65) | ADRB1ADRB3ADRB2MEN1ALDH1A1 | |
| SCHEMBL9684248 | 0.85 | ADRB1 (0.65) | ADRB1ADRB3ADRB2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9683322 | 0.85 | ADRB3 (0.64) | ADRB1ADRB3ADRB2MEN1ALDH1A1 | |
| SCHEMBL9685359 | 0.85 | ADRB3 (0.64) | ADRB1ADRB3ADRB2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9683325 | 0.85 | ADRB3 (0.64) | ADRB1ADRB3ADRB2MEN1ALDH1A1 | |
| SCHEMBL9685355 | 0.85 | ADRB3 (0.64) | ADRB1ADRB3ADRB2MEN1ALDH1A1 | |
| SCHEMBL9787387 | 0.83 | ADRB1 (0.49) | ADRB1ADRB3ADRB2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |