Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | AHCY | P23526 | 5/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684215 | 0.86 | ADORA2A (0.40) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9685561 | 0.86 | CYP3A4 (0.47) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9685345 | 0.86 | CDK1 (0.40) | CYP3A4FGFR1SLC22A6AHCY | |
| SCHEMBL9685592 | 0.83 | CYP3A4 (0.47) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9675613 | 0.81 | CYP3A4 (0.44) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9417190 | 0.80 | CYP3A4 (0.55) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9555564 | 0.80 | CYP3A4 (0.55) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9555809 | 0.80 | CYP3A4 (0.55) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9684414 | 0.79 | HPRT1 (0.56) | — | |
| SCHEMBL9685282 | 0.79 | FGFR1 (0.53) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |
| EP-0365917-A1 | Polymer mixtures | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |