SCHEMBL9685594

SCHEMBL9685594

Cc1ccccc1[SiH](O)COc1ccccc1OC[SiH](O)c1ccccc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.39
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
ALDH1A1 P00352 2/20 0.36
GLA P06280 1/20 0.36
ALOX15 P16050 1/20 0.36
NOTUM Q6P988 1/20 0.35
AOC2 O75106 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
LMNA P02545 3/20 0.34
MAPT P10636 2/20 0.34
JAK2 O60674 1/20 0.34
GAA P10253 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
SCN4A P35499 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13720383 0.74 ACHE (0.39) ALDH1A1MAOAMAOBMAPTTDP1
SCHEMBL272693 0.69 TSHR (0.35) KDM4ECYP1A2ALDH1A1MAOAMAOB
SCHEMBL271788 0.68 TSHR (0.47) KDM4ECYP1A2ALDH1A1ALOX15MAOA
SCHEMBL27943186 0.66 TSHR (0.45) KDM4ECYP1A2ALDH1A1ALOX15LMNA
SCHEMBL15641904 0.65 TSHR (0.43) CYP1A2ALDH1A1MAOAMAOBTDP1
SCHEMBL2274332 0.64 ACHE (0.38) KDM4ECYP1A2ALDH1A1ALOX15LMNA
SCHEMBL792553 0.63 KDM4E (0.60) KDM4ECYP1A2RXRARXRBRXRG
SCHEMBL13069720 0.63 ALDH1A1 (0.52) KDM4ECYP1A2RXRARXRBRXRG
SCHEMBL1557214 0.62 TSHR (0.53) CYP1A2ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL3301718 0.62 TSHR (0.45) CYP1A2ALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096991-A Monomer from dihydroxy aromatic compound and haloalkylsilanol, elasticity, strength SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-03-17 US disclosed