Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 6/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9685650 | 0.90 | DPP4 (0.46) | DHFRDPP4CHRM2DRD1LMNA | |
| Hydrochloric Acid SCHEMBL9686908 | 0.89 | LMNA (0.51) | DHFRDPP4CHRM2DRD1LMNA | |
| SCHEMBL10378901 | 0.89 | DPP4 (0.49) | DHFRDPP4CHRM2DRD1LMNA | |
| SCHEMBL9686492 | 0.88 | DHFR (0.59) | DHFRDPP4CHRM2DRD1LMNA | |
| Hydrochloric Acid SCHEMBL10916126 | 0.88 | DPP4 (0.49) | DHFRDPP4CHRM2DRD1LMNA | |
| SCHEMBL10377709 | 0.88 | DPP4 (0.51) | DHFRDPP4CHRM2DRD1LMNA | |
| Hydrochloric Acid SCHEMBL9686519 | 0.88 | DPP4 (0.47) | DHFRDPP4CHRM2DRD1LMNA | |
| SCHEMBL10377270 | 0.87 | DPP4 (0.50) | DHFRDPP4CHRM2DRD1LMNA | |
| SCHEMBL10377338 | 0.87 | DPP4 (0.50) | DHFRDPP4CHRM2DRD1LMNA | |
| SCHEMBL9687317 | 0.85 | DPP4 (0.49) | DHFRDPP4CHRM2DRD1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187376-B1 | 6,7-DISUBSTITUTED 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS | BAYER AG (DE) | 1992-05-13 | — | — | EP | claimed |
| EP-0187376-B1 | 6,7-DISUBSTITUTED 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |