Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.71 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.70 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.47 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484426 | 0.84 | PDE3B (0.68) | PGRPDE3BPDE3AGRIA1CACNG8 | |
| SCHEMBL6541883 | 0.83 | PGR (1.00) | PGRPDE3BPDE3AGRIA1CACNG8 | |
| SCHEMBL2439269 | 0.82 | PDE3B (0.66) | PGRPDE3BPDE3AGRIA1CACNG8 | |
| SCHEMBL6909727 | 0.80 | PDE3B (0.68) | PGRPDE3BPDE3APIK3CAPI4KA | |
| SCHEMBL9685722 | 0.80 | PDE3B (0.76) | PGRPDE3BPDE3AGRIA1CACNG8 | |
| SCHEMBL11187529 | 0.78 | PGR (0.61) | PGRPDE3BPDE3AGRIA1CACNG8 | |
| SCHEMBL6541670 | 0.78 | PGR (1.00) | PGRPDE3BPDE3ASMN1; SMN2NPC1 | |
| SCHEMBL11539227 | 0.77 | PIM1 (0.47) | PGRPDE3BPDE3ATNKS2SMN1; SMN2 | |
| SCHEMBL83411 | 0.76 | CMA1 (0.59) | PGRPDE3BPDE3ACMA1HTR1A | |
| SCHEMBL29667911 | 0.76 | CMA1 (0.59) | PGRPDE3BPDE3ACMA1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |