Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.76 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.76 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848088 | 0.86 | PDE3B (1.00) | PDE3BPDE3APGRPSMB8ALDH1A1 | |
| SCHEMBL9484426 | 0.81 | PDE3B (0.68) | PDE3BPDE3APGRALDH1A1SMN1; SMN2 | |
| SCHEMBL9685728 | 0.80 | PDE3B (0.69) | PDE3BPDE3APSMB8ALDH1A1SMN1; SMN2 | |
| SCHEMBL9685741 | 0.80 | PGR (0.71) | PDE3BPDE3APGRSMN1; SMN2NPC1 | |
| SCHEMBL9483327 | 0.79 | PDE3B (0.68) | PDE3BPDE3APSMB8ALDH1A1SMN1; SMN2 | |
| SCHEMBL8799197 | 0.78 | PDE3B (0.77) | PDE3BPDE3APSMB8ALDH1A1SMN1; SMN2 | |
| SCHEMBL9484783 | 0.78 | PDE3B (0.66) | PDE3BPDE3APSMB8ALDH1A1SMN1; SMN2 | |
| SCHEMBL2439269 | 0.77 | PDE3B (0.66) | PDE3BPDE3APGRALDH1A1GRIA1 | |
| SCHEMBL11213147 | 0.72 | PDE3B (0.68) | PDE3BPDE3APSMB8ALDH1A1KDM4E | |
| SCHEMBL3363620 | 0.72 | KDM4E (0.70) | ALDH1A1SMN1; SMN2KDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |