Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | HTR2C | P28335 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947871 | 0.92 | DRD2 (0.48) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL8871094 | 0.88 | HTR1A (0.42) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL9685780 | 0.86 | HTR1A (0.50) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL175879 | 0.84 | HTR1A (0.51) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL9684901 | 0.82 | PDE3B (0.51) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL8786271 | 0.79 | HTR1A (0.48) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL1324801 | 0.77 | HTR1A (0.49) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL1325447 | 0.77 | HTR1A (0.49) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL4882695 | 0.76 | HTR1A (0.51) | HTR1AHTR2CMAPTPDE3BPDE3A | |
| SCHEMBL9684687 | 0.76 | HTR1A (0.46) | HTR1AHTR2CMAPTPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | disclosed |
| US-5512569-A | SIGMA RECEPTOR DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-04-30 | — | — | US | disclosed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |