Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 8/20 | 0.51 |
| ▸ | HTR2C | P28335 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685780 | 0.90 | HTR1A (0.50) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL175879 | 0.89 | HTR1A (0.51) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL9204486 | 0.86 | MAPT (0.59) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL8947871 | 0.85 | DRD2 (0.48) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL7332557 | 0.83 | HTR1A (0.51) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL4882695 | 0.83 | HTR1A (0.51) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL17080919 | 0.83 | HTR1A (0.51) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL7762986 | 0.82 | HTR1A (0.45) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL9658547 | 0.82 | HTR1A (0.48) | PDE3BPDE3AHTR1AHTR2CMAPT | |
| SCHEMBL9685616 | 0.81 | HTR1A (0.60) | PDE3BPDE3AHTR1AHTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |