SCHEMBL9685854

SCHEMBL9685854

Fc1[c]cc(Oc2ccccc2F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.47
LPAR1 Q92633 4/20 0.37
LPAR5 Q9H1C0 4/20 0.37
DAO P14920 1/20 0.37
HTR1A P08908 4/20 0.37
SLC6A2 P23975 4/20 0.37
SLC6A3 Q01959 3/20 0.37
ALDH1A1 P00352 2/20 0.37
ESR1 P03372 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CXCL8 P10145 1/20 0.37
RHEB Q15382 1/20 0.36
FAAH O00519 1/20 0.36
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SLC6A4 P31645 1/20 0.34
GCK P35557 1/20 0.34
MMP14 P50281 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27804084 0.82 PARP10 (0.49) PARP10LPAR1LPAR5DAOHTR1A
SCHEMBL6293051 0.80 PARP10 (0.66) PARP10LPAR1LPAR5DAOHTR1A
SCHEMBL920067 0.79 LTA4H (0.50) PARP10MEN1KMT2A
SCHEMBL6289863 0.78 PARP10 (0.63) PARP10LPAR1LPAR5DAOHTR1A
SCHEMBL9684602 0.76 SOS1 (0.42) ALDH1A1MEN1KMT2AHTTL3MBTL1
SCHEMBL6290343 0.76 PARP10 (0.61) PARP10LPAR1LPAR5DAOHTR1A
SCHEMBL6293904 0.76 PARP10 (0.61) PARP10LPAR1LPAR5DAOHTR1A
SCHEMBL2458461 0.76 PARP10 (0.61) PARP10LPAR1LPAR5DAOHTR1A
SCHEMBL6293879 0.76 PARP10 (0.61) PARP10LPAR1LPAR5DAOHTR1A
SCHEMBL919864 0.74 PARP10 (0.44) PARP10LPAR1LPAR5DAOHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1044661-C Pesticides, insecticides, miticides and nematocides compositions containing new silanes derivatives HOECHST AG (DE) 1999-08-18 CN disclosed
CN-1032005-C Novel silane derivatives, formulations containing them and their use as pesticides HOECHST AG (DE) 1996-06-12 CN disclosed
CN-1027448-C Heterocyclic neophenan analogs and their use as anti-inflammatory agents HOECHST AG (DE) 1995-01-18 CN disclosed
CN-1091425-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides HOECHST AG (DE) 1994-08-31 CN disclosed
CN-1025470-C Pesticide, insecticide and acaricide compositions containing novel silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1025502-C Process for preparing silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1025501-C Process for preparing silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1077588-A The agricultural chemicals, insecticide, the acaricidal nematicidal agent composition that contain novel silane derivs HOECHST AG (DE) 1993-10-27 CN disclosed
EP-0288810-B1 HETEROCYCLIC NEOPHANE ANALOGS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-02 EP disclosed
US-5116826-A SILAZANEOPHYL SULFIDES, AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
EP-0224024-B1 SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-20 EP disclosed
EP-0336199-A1 Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed
US-4864027-A INSECTICIDES, NEMATOCIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-05 US disclosed
EP-0288810-A1 Heterocyclic neophane analogs, processes for their preparation and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-02 EP disclosed
CN-88102112-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides 1988-10-26 CN disclosed
US-4775664-A INSECTICIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-10-04 US disclosed
CN-87102981-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1988-03-02 CN disclosed
EP-0249015-A1 Silane derivatives, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-16 EP disclosed
CN-86107292-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1987-07-29 CN disclosed
EP-0224024-A1 Silane derivatives, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed