SCHEMBL9684602

SCHEMBL9684602

Fc1[c]cc(Oc2ccc(F)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.42
HSPB1 P04792 1/20 0.42
SCN4A P35499 3/20 0.38
GAA P10253 1/20 0.36
LTA4H P09960 4/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
EPHX2 P34913 2/20 0.34
FFAR1 O14842 2/20 0.34
FFAR4 Q5NUL3 1/20 0.34
SCN9A Q15858 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HTT P42858 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920067 0.85 LTA4H (0.50) SOS1LTA4HMEN1KMT2A
SCHEMBL27782489 0.79 SOS1 (0.44) SOS1HSPB1SCN4AGAALTA4H
SCHEMBL9686282 0.79 MMP14 (0.40) GAAMEN1KMT2AKDM4EFFAR1
SCHEMBL6290683 0.78 SOS1 (0.58) SOS1HSPB1SCN4AGAALTA4H
SCHEMBL6289867 0.78 SOS1 (0.58) SOS1HSPB1SCN4AGAALTA4H
SCHEMBL351854 0.78 SOS1 (0.58) SOS1HSPB1SCN4AGAALTA4H
SCHEMBL9685854 0.76 PARP10 (0.47) MEN1KMT2AFFAR1L3MBTL1HTT
SCHEMBL7367702 0.75 SOS1 (0.56) SOS1HSPB1SCN4AGAALTA4H
SCHEMBL3518 0.73
SCHEMBL163245 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101528685-B New benzamide derivatives as bradykinin antagonists RICHTER GEDEON NYRT 2012-09-05 CN disclosed
CN-1044661-C Pesticides, insecticides, miticides and nematocides compositions containing new silanes derivatives HOECHST AG (DE) 1999-08-18 CN disclosed
CN-1032005-C Novel silane derivatives, formulations containing them and their use as pesticides HOECHST AG (DE) 1996-06-12 CN disclosed
CN-1027448-C Heterocyclic neophenan analogs and their use as anti-inflammatory agents HOECHST AG (DE) 1995-01-18 CN disclosed
CN-1091425-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides HOECHST AG (DE) 1994-08-31 CN disclosed
CN-1025502-C Process for preparing silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1025470-C Pesticide, insecticide and acaricide compositions containing novel silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1025501-C Process for preparing silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1077588-A The agricultural chemicals, insecticide, the acaricidal nematicidal agent composition that contain novel silane derivs HOECHST AG (DE) 1993-10-27 CN disclosed
EP-0288810-B1 HETEROCYCLIC NEOPHANE ANALOGS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-02 EP disclosed
EP-0224024-B1 SILANE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-20 EP disclosed
EP-0336199-A1 Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed
US-4864027-A INSECTICIDES, NEMATOCIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-05 US disclosed
EP-0288810-A1 Heterocyclic neophane analogs, processes for their preparation and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-02 EP disclosed
CN-88102112-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides 1988-10-26 CN disclosed
US-4775664-A INSECTICIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-10-04 US disclosed
CN-87102981-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1988-03-02 CN disclosed
EP-0249015-A1 Silane derivatives, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-16 EP disclosed
CN-86107292-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1987-07-29 CN disclosed
EP-0224024-A1 Silane derivatives, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed