Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685002 | 0.88 | GLRA3 (0.46) | KDM4EALDH1A1TSHRSMN1; SMN2GAA | |
| SCHEMBL11014994 | 0.78 | KDM4E (0.89) | KDM4EALDH1A1TSHRSMN1; SMN2GAA | |
| SCHEMBL29173863 | 0.78 | ADORA3 (0.82) | KDM4EALDH1A1TSHRSMN1; SMN2GAA | |
| SCHEMBL7267309 | 0.77 | KDM4E (0.72) | KDM4EALDH1A1TSHRSMN1; SMN2GAA | |
| SCHEMBL7815204 | 0.74 | KDM4E (0.72) | KDM4EALDH1A1TSHRSMN1; SMN2GAA | |
| SCHEMBL7817206 | 0.74 | KDM4E (0.88) | KDM4EALDH1A1TSHRSMN1; SMN2GAA | |
| SCHEMBL3022545 | 0.73 | ABCC1 (0.74) | KDM4EALDH1A1TSHRSMN1; SMN2GAA | |
| SCHEMBL7266484 | 0.73 | CACNA1B (0.73) | ADORA3ABCC1CACNA1BCACNA1FCACNA1D | |
| SCHEMBL7275780 | 0.73 | CACNA1F (0.67) | KDM4EALDH1A1TSHRSMN1; SMN2ADORA3 | |
| SCHEMBL3027412 | 0.73 | ADORA3 (0.89) | KDM4EALDH1A1TSHRSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500426-A1 | 2,6-Dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine derivatives, process for their preparation and their use as free radical scavengers | Instituto de Investigacion Y Desarrollo Quimico-Biologico S.A. (ES) | 1992-08-26 | — | — | EP | claimed |
| EP-0500426-A1 | 2,6-Dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine derivatives, process for their preparation and their use as free radical scavengers | Instituto de Investigacion Y Desarrollo Quimico-Biologico S.A. (ES) | 1992-08-26 | — | — | EP | disclosed |