Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.46 |
| ▸ | GLRB | P48167 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686036 | 0.88 | KDM4E (0.55) | GAAALDH1A1SMN1; SMN2POLBCACNA1B | |
| SCHEMBL7821234 | 0.74 | KDM4E (0.47) | GAAALDH1A1SMN1; SMN2CA2POLB | |
| SCHEMBL30932230 | 0.71 | ALDH1A1 (0.64) | GAAALDH1A1SMN1; SMN2POLBCACNA1B | |
| SCHEMBL9688157 | 0.71 | KDM4E (0.49) | GAAALDH1A1SMN1; SMN2CACNA1BHTT | |
| SCHEMBL9580241 | 0.70 | CA2 (0.48) | GLRA3GLRBGAAALDH1A1SMN1; SMN2 | |
| Hydrazine SCHEMBL9180071 | 0.69 | GLRA3 (0.59) | GLRA3GLRBGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL227202 | 0.68 | GLRA3 (0.63) | GLRA3GLRBGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7341175 | 0.68 | CACNA1B (0.64) | CACNA1B | |
| SCHEMBL8949674 | 0.67 | CACNA1F (0.53) | GAAALDH1A1SMN1; SMN2POLBCACNA1B | |
| SCHEMBL4789805 | 0.67 | LMNA (0.48) | GAAALDH1A1SMN1; SMN2POLBCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500426-A1 | 2,6-Dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine derivatives, process for their preparation and their use as free radical scavengers | Instituto de Investigacion Y Desarrollo Quimico-Biologico S.A. (ES) | 1992-08-26 | — | — | EP | claimed |
| EP-0500426-A1 | 2,6-Dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine derivatives, process for their preparation and their use as free radical scavengers | Instituto de Investigacion Y Desarrollo Quimico-Biologico S.A. (ES) | 1992-08-26 | — | — | EP | disclosed |