Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.45 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686090 | 0.84 | ADCY5 (0.47) | NT5EADCY5P2RY1 | |
| SCHEMBL9685235 | 0.84 | ADCY5 (0.64) | ADORA1ADCY5ADORA3 | |
| SCHEMBL9704183 | 0.83 | ADORA3 (0.55) | ADORA1ADORA3 | |
| SCHEMBL9704176 | 0.83 | YTHDC1 (0.49) | ADCY5ADORA3 | |
| SCHEMBL21839481 | 0.79 | NT5E (0.77) | NT5ETAS1R3TAS1R1ADORA1GPR17 | |
| SCHEMBL30394506 | 0.79 | NT5E (0.77) | NT5ETAS1R3TAS1R1ADORA1GPR17 | |
| SCHEMBL21883307 | 0.77 | TAS1R3 (0.60) | NT5ETAS1R3TAS1R1ADORA1GPR17 | |
| SCHEMBL9686031 | 0.77 | ADORA3 (0.47) | TAS1R3TAS1R1ADORA1CCNA2CDK2 | |
| SCHEMBL21883308 | 0.77 | TAS1R3 (0.61) | NT5ETAS1R3TAS1R1ADORA1GPR17 | |
| SCHEMBL21839754 | 0.75 | TAS1R3 (0.81) | NT5ETAS1R3TAS1R1ADORA1GPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468866-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0468119-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |