Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 10/20 | 0.58 |
| ▸ | ACACA | Q13085 | 8/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685836 | 0.79 | ACACB (0.66) | ACACBACACAALOX5 | |
| SCHEMBL12001374 | 0.75 | ACACB (0.92) | ACACBACACA | |
| SCHEMBL27513379 | 0.74 | GPR88 (0.57) | SMN1; SMN2MAPK1 | |
| SCHEMBL254946 | 0.74 | MAPK1 (0.58) | SMN1; SMN2MAPK1 | |
| SCHEMBL256332 | 0.73 | ACACB (1.00) | ACACBACACA | |
| SCHEMBL12001364 | 0.73 | ACACB (1.00) | ACACBACACA | |
| SCHEMBL14599721 | 0.73 | GPR88 (0.59) | SMN1; SMN2MAPK1 | |
| SCHEMBL10705448 | 0.73 | ALOX5 (0.59) | ACACBALOX5HDAC10HDAC6 | |
| SCHEMBL8120294 | 0.72 | HDAC10 (0.60) | SMN1; SMN2MAPK1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL15542046 | 0.72 | SMN1; SMN2 (0.55) | ACACBACACASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990008545-A1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-08-09 | — | — | WO | claimed |
| US-5175183-A | Antiinflammatory agents, respiratory system disorders | ABBOTT LABORATORIES (US) | 1992-12-29 | — | — | US | disclosed |
| WO-1990008545-A1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-08-09 | — | — | WO | disclosed |