Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.66 |
| ▸ | ACACA | Q13085 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668698 | 0.87 | ACACB (0.63) | ACACBACACAALOX5F7LTA4H | |
| SCHEMBL9398051 | 0.83 | ACACB (0.60) | ACACBALOX5LTA4H | |
| SCHEMBL9686116 | 0.82 | ACACB (0.67) | ACACBACACAALOX5LTA4H | |
| SCHEMBL9474891 | 0.81 | ACACB (0.65) | ACACBACACAALOX5F7LTA4H | |
| SCHEMBL3425496 | 0.80 | ACACB (0.64) | ACACBACACAALOX5F7LTA4H | |
| SCHEMBL9686091 | 0.79 | ACACB (0.58) | ACACBACACAALOX5 | |
| SCHEMBL10426966 | 0.78 | ACACB (0.58) | ACACBALOX5LTA4H | |
| Hydroxyurea SCHEMBL9474720 | 0.77 | ALOX5 (0.60) | ACACBALOX5LTA4H | |
| Hydroxyurea SCHEMBL9475017 | 0.77 | ALOX5 (0.60) | ACACBALOX5LTA4H | |
| SCHEMBL2885897 | 0.77 | ALOX5 (0.62) | ACACBALOX5LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990008545-A1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-08-09 | — | — | WO | claimed |
| US-5175183-A | Antiinflammatory agents, respiratory system disorders | ABBOTT LABORATORIES (US) | 1992-12-29 | — | — | US | disclosed |
| WO-1990008545-A1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-08-09 | — | — | WO | disclosed |