Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | BID | P55957 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942508 | 0.83 | SIRT1 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29435080 | 0.83 | SIRT1 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9685276 | 0.80 | CA12 (0.66) | CA12CA1CA2CA7CA9 | |
| SCHEMBL487237 | 0.79 | SIRT1 (0.50) | CA12CA2CA14SIRT1TDP1 | |
| SCHEMBL13953924 | 0.79 | CYP2C9 (0.49) | SIRT1TDP1MAPTALDH1A1HPGD | |
| SCHEMBL19045041 | 0.79 | TDP1 (0.51) | SIRT1TDP1MAPTKDM4ENSD2 | |
| SCHEMBL2853747 | 0.78 | SIRT1 (0.47) | SIRT1TDP1MAPTKDM4ENSD2 | |
| SCHEMBL595125 | 0.78 | ALDH1A1 (0.46) | CA12CA1CA2CA14SIRT1 | |
| SCHEMBL19045039 | 0.76 | TDP1 (0.59) | TDP1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5603402 | 0.76 | CA1 (1.00) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100458-A | Pyrimidine substituted, plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| EP-0435104-A2 | Salicylic acid derivatives, process for their preparation and their use as herbicide and bioregulators | BASF Aktiengesellschaft (DE) | 1991-07-03 | — | — | EP | disclosed |