SCHEMBL487237

SCHEMBL487237

Oc1ccccc1Sc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT1 Q96EB6 1/20 0.50
MAPT P10636 4/20 0.44
TDP1 Q9NUW8 3/20 0.44
KDM4E B2RXH2 2/20 0.44
NSD2 O96028 1/20 0.44
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 4/20 0.43
HPGD P15428 4/20 0.43
L3MBTL1 Q9Y468 4/20 0.43
BLM P54132 2/20 0.43
LMNA P02545 2/20 0.43
ALOX15 P16050 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HSD17B10 Q99714 2/20 0.43
NPC1 O15118 1/20 0.43
CA12 O43570 1/20 0.43
GMNN O75496 1/20 0.43
EGFR P00533 1/20 0.43
CA2 P00918 1/20 0.43
FYN P06241 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5399446 0.86 NR1H2 (0.56) SIRT1MAPTTDP1KDM4EALDH1A1
SCHEMBL595125 0.84 ALDH1A1 (0.46) SIRT1MAPTTDP1KDM4ENSD2
SCHEMBL11205285 0.84 ALOX15 (0.53) MAPTTDP1KDM4EALDH1A1HPGD
SCHEMBL31339525 0.84 ALOX15 (0.53) MAPTTDP1KDM4EALDH1A1HPGD
SCHEMBL69003 0.84 ALOX15 (0.53) MAPTTDP1KDM4EALDH1A1HPGD
SCHEMBL13048915 0.82 MAPT (0.47) MAPTTDP1ALDH1A1HPGDL3MBTL1
SCHEMBL28647118 0.82 ALDH1A1 (0.45) SIRT1MAPTTDP1KDM4EMAPK1
SCHEMBL3893766 0.82 SIRT1 (0.36) SIRT1MAPTTDP1KDM4ENSD2
SCHEMBL10616298 0.82 HPGD (0.53) SIRT1MAPTTDP1KDM4EMAPK1
SCHEMBL7539703 0.82 PKM (0.49) SIRT1MAPTTDP1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113083350-B Preparation method and application of Cu/Al-SBA-15 bimetal composite catalyst 三峡大学 2022-08-05 CN claimed
CN-113083349-A Preparation method and application of SBA-15 modified by nano Cu simple substance 三峡大学 2021-07-09 CN claimed
CN-113083350-A Preparation method and application of Cu/Al-SBA-15 bimetal composite catalyst 三峡大学 2021-07-09 CN claimed
CN-109988087-B Method for preparing 2-phenyl sulfoxide phenol compound by multi-component reaction 浙江农林大学暨阳学院 2020-12-01 CN claimed
EP-0777716-A2 SURFACE-ACTIVE FORMULATIONS Ciba SC Holding AG (CH) 1997-06-11 EP claimed
WO-1996006152-A2 SURFACE-ACTIVE FORMULATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-02-29 WO claimed
CN-117802511-A Preparation method of thiosulfate compound 西华大学 2024-04-02 CN disclosed
CN-113574041-B Bisphenol production method and polycarbonate resin production method 三菱化学株式会社 2023-10-13 CN disclosed
CN-113083350-B Preparation method and application of Cu/Al-SBA-15 bimetal composite catalyst 三峡大学 2022-08-05 CN disclosed
CN-113083350-A Preparation method and application of Cu/Al-SBA-15 bimetal composite catalyst 三峡大学 2021-07-09 CN disclosed
CN-109988087-B Method for preparing 2-phenyl sulfoxide phenol compound by multi-component reaction 浙江农林大学暨阳学院 2020-12-01 CN disclosed
WO-2020189201-A1 METHOD FOR PRODUCING BISPHENOL AND METHOD FOR PRODUCING POLYCARBONATE RESIN 三菱ケミカル株式会社 2020-09-24 WO disclosed
US-10173975-B2 Sulfonium compound, resist composition, and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-01-08 US disclosed
EP-0084578-A1 Copolycarbonates having high melt flow rates Mobay Chemical Corporation (US) 1983-08-03 EP disclosed
US-4275249-A ALUMINA ALKYLATION CATALYST CONTAINING FLUORIDE OR CHLORIDE CATALYST UOP INC. (US) 1981-06-23 US disclosed
US-4275248-A CATALYTIC ALKYLATION OF PHENOL WITH PROPYLENE USING FLUORIDED ALUMINA AS CATALYST UOP INC. (US) 1981-06-23 US disclosed
US-4260833-A Preparation of alkylphenols UOP INC. (US) 1981-04-07 US disclosed
US-4060612-A ANTIDEPRESSANT MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1977-11-29 US disclosed
US-4025399-A ELECTRICAL, RECORDING LAYER WITH A CONDUCTIVE AGENT, A LEUCO BASE AND A PHENOLIC RESIN CANON KABUSHIKI KAISHA (JA) 1977-05-24 US disclosed
US-3947468-A Production of dibenzopyrans, their isomeric fluorenols and dibenzothiopyrans GENERAL ELECTRIC COMPANY (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10173975-B2 Sulfonium compound, resist composition, and pattern forming process C1R, LBR, SMARCC2 SIRT1 4286/4885MAPT 4225/4885TDP1 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.