Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | FADS1 | O60427 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10112873 | 0.84 | ALDH1A1 (0.50) | RECQLKMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL6351799 | 0.80 | RECQL (0.64) | RECQLFADS1GFERKMT2ASMN1; SMN2 | |
| SCHEMBL9540049 | 0.79 | RECQL (0.79) | RECQLFADS1GFERKMT2ASMN1; SMN2 | |
| SCHEMBL145366 | 0.78 | RECQL (0.67) | RECQLGFERKMT2ASMN1; SMN2MAPT | |
| SCHEMBL31000389 | 0.78 | RECQL (0.67) | RECQLGFERKMT2ASMN1; SMN2MAPT | |
| SCHEMBL30484136 | 0.78 | RECQL (0.67) | RECQLGFERKMT2ASMN1; SMN2MAPT | |
| SCHEMBL12653273 | 0.77 | RECQL (0.60) | RECQLFADS1GFERKMT2ASMN1; SMN2 | |
| SCHEMBL6341269 | 0.77 | RECQL (0.60) | RECQLFADS1GFERKMT2ASMN1; SMN2 | |
| Hydrazine SCHEMBL11821861 | 0.77 | RECQL (0.65) | RECQLGFERKMT2ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL27581315 | 0.77 | RECQL (0.65) | RECQLGFERKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491218-A1 | Benzodiazepinones | F. HOFFMANN-LA ROCHE AG (CH) | 1992-06-24 | — | — | EP | disclosed |