Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DDX3X | O00571 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687020 | 0.85 | ALDH1A1 (0.56) | ALDH1A1RECQLSMN1; SMN2POLBTDP1 | |
| SCHEMBL8192482 | 0.85 | RAB9A (0.44) | ALDH1A1POLBDDX3XITGB3ITGAV | |
| SCHEMBL9687629 | 0.83 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL9685711 | 0.82 | POLB (0.50) | ALDH1A1POLBDDX3XITGB3ITGAV | |
| SCHEMBL5901959 | 0.82 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AKMT2AHPGD | |
| SCHEMBL9686578 | 0.81 | HPGD (0.45) | ALDH1A1SMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL9687443 | 0.78 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL14401688 | 0.78 | ALDH1A1 (0.60) | ALDH1A1RECQLSMN1; SMN2POLBTDP1 | |
| SCHEMBL8369698 | 0.77 | ALDH1A1 (0.76) | ALDH1A1RECQLSMN1; SMN2POLBDDX3X | |
| SCHEMBL9687657 | 0.76 | HPGD (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |